In May this year there were 44,000 jobs listed in regional Australia, with 900 of those in regional SA.
Regional Development SA chair Rob Kerin said SA was experiencing a growing labour and skills shortage in parts of the state.
"We have the highest economic reliance on regions of all states but also the highest concentration of population in the city," he said.
"It's about skilled workers and a labour force, not cheap labour.
"We need the labour, otherwise we can lose investment."
Employers say jobs such as mechanics, bakers and more are remaining open, while many communities know of the case of missing doctors and other health professionals.
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